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Three different coronavirus shots – those mainly available in the US and Europe – have shown a dramatic decline in efficacy over time, a study of nearly 800,000 Americans reveals. Covid-19 vaccine effectiveness against both infection and death was studied in three US approved jabs – the Pfizer-BioNTech and Moderna mRNA shots, and the Janssen viral vector vaccine.

Having analyzed data from 780,225 US veterans of different ages and sexes, researchers came to a disturbing conclusion. Vaccine protection against Covid-19 infection dropped from 89.2% at its highest to a low of 13.1%... by September there were massive declines to 58%, 43%, and 13% respectively. The emergence and dominance of the Delta strain of the virus during the time of the study may have played a role, researchers said, adding that vaccine protection waned across all studied age groups.

On a brighter note, vaccine effectiveness against hospitalization and death remained high. As breakthrough infections, hospitalizations, and deaths continue to emerge in fully vaccinated people, there is "an urgent need to reinstate multiple layers of protection, such as masking and physical distancing – even among vaccinated persons," the scientists warn.